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Zetia

Zetia (generic name ezetimibe) is a cholesterol medication used to lower levels of total cholesterol and LDL (bad) cholesterol in the blood. It is used for patients who cannot control their cholesterol levels by diet alone. It can be used by itself or with certain other medicines to treat high cholesterol. By lowering cholesterol levels better than older medications called statins can do alone, Zetia is meant to help better prevent the development of arterial plaque, which can lead to heart disease and heart attacks.

However, an extensive study completed in mid 2006, and released in January 2008 has shown that taking Zetia had no benefit on the buildup of arterial plaque when compared with patients taking only statins such as Zocor. This finding is significant, as Zetia is more expensive than the generic version of Zocor (simvastatin). The manufacturer has disputed the study's findings, but within weeks of the study's release a class action lawsuit has already been filed against Merck and Schering-Plough. The Zetia lawsuit alleges that the companies have known since 2006 that their drug was no more effective than the cheaper generic Zocor, despite leading consumers to believe the opposite.

Fast Facts

Name: Zetia
Generic: Ezetimibe
Manufacturer: Merck/Schering-Plough
Date approved: October 25, 2002
Status: Prescription only
Approved uses: Treatment for patients who cannot control their cholesterol levels by diet alone
Off-Label uses: None at present
Side effects: Stomach pain, tiredness, joint pain, muscle problems (muscle pain, tenderness, or weakness) and possible allergic reaction
Related topics: Vytorin

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Zetia Does Not Reduce Heart Attack Risk

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FDA Information Related to Zetia

FDA and VA to Share Information on the Safe Use of Medical Products

FDA Reinforces Commitment to Drug Safety

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MSN Newsfeeds Related to Zetia

UPDATE 1-Schering-Plough CEO to buy $2 mln in stock

News Review From Harvard Medical School -- Weak Depression-Drug Data ...

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News Articles Related to Zetia

Vytorin Results Disappointing, Experts Say Don't Panic

Study Deals Setback to Cholesterol Drug - WSJ.com

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Wikipedia Entries Related to Zetia

Ezetimibe

Cholesterol

View the Zetia Wikipedia Entries page here


Books Related to Zetia

Nicostatin, rosuvastatin, ezetimibe to debut soon. (Excellent Safety Profiles). : An article from: Internal Medicine News

Ezetimibe further cuts Statin's LDL declines by 15%: Ezetimibe may help patients who fail to reach cholesterol targets on statins alone. (Under FDA Review). : An article from: Internal Medicine News

View the Zetia Books page here

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